Rethinking the genetic architecture of schizophrenia
نویسندگان
چکیده
منابع مشابه
Rethinking the genetic architecture of schizophrenia.
BACKGROUND For many years, the prevailing paradigm has stated that in each individual with schizophrenia (SZ) the genetic risk is due to a combination of many genetic variants, individually of small effect. Recent empirical data are prompting a re-evaluation of this polygenic, common disease-common variant (CDCV) model. Evidence includes a lack of the expected strong positive findings from geno...
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ژورنال
عنوان ژورنال: Psychological Medicine
سال: 2010
ISSN: 0033-2917,1469-8978
DOI: 10.1017/s003329171000070x